The Orbitrap Fusion Tribrid 質譜儀使科學家能夠分析更具挑戰性的低豐度、高複雜性樣品，並能更快地識別更多化合物，同時定量更準確，結構解析更透徹。
絕佳的性能
超高分辨率，高達 500,000 FWHM，可消除幹擾
母離子選擇使用四極杆質量過濾器，使離子阱和 Orbitrap 質量分析器可以並行操作，以獲得出色的靈敏度和選擇性
多重解離技術——CID、HCD 和可選 ETD——配有離子阱或 Orbitrap 檢測可以在任何 MSn 級別進行檢測，最大程度提高其在研究應用中的靈活性
碎片的靈活性——CID-HCD、HCD-CID 和 HCD-HCD——在 MSn 分析的任何階段與任一質量分析器檢測的碎片離子一起，可以對代謝物、多糖和其他小分子進行詳細的結構測定
帶軸向場的主動離子束傳輸組件可以降低噪聲並增加耐用性
新型 Orbitrap 分析儀設計和雙壓離子阱配置可以提供快速 MS/MS 掃描，掃描率高達 20 Hz，具有無與倫比的譜圖質量
Thermo Scientific™ Easy-Max NG™ 與可選的 Thermo Scientific™ Ion Max NG™ 及 Nanospray Flex NG™ 離子源均為具有下一代性能的離子源
易於使用
動態掃描管理幫助用戶輕鬆獲得樣品的最多信息，最有效地安排掃描事件，並使用最佳裂解模式和質量分析器智能匹配每個母離子
適合通用實驗的默認特定應用模板庫可以簡化方法開發過程
兼容 Thermo Scientific™ Compound Discoverer™、Mass Frontier™、Pinpoint™、Protein Deconvolution、Proteome Discoverer™、ProSightPC 和 SIEVE™ 軟件以提升特定應用的生產率
性能參數：
Mass Range
Linear Ion Trap and Orbitrap Mass Range:
Standard – m/z 50–2,000
High Mass – m/z 200–4,000
Orbitrap Extended Mass Range:
Up to m/z 6000 without precursor ion selection
Resolution
15,000-450,000 (FWHM) at m/z 200
Scan Rate
Orbitrap MSn up to 20 Hz
Ion trap MSn up to 20 Hz
Mass Accuracy
< 3 ppm RMS using external calibration
< 1 ppm RMS using internal calibration
MS/MS Sensitivity of Ion Trap
2 μL of a 50 fg/μL solution of reserpine (100 fg total) injected at a flow of 500 μL/min will produce a minimum signal-to-noise ratio of 100:1 for the transition of the isolated protonated molecular ions at m/z 609 to the largest two product ions, m/z 397 and m/z 448, when the mass spectrometer is operated at unit resolution in the full-scan MS/MS mode, m/z 165–615. The test requires the HESI probe.
Dynamic Range
> 5,000 within a single scan, guaranteeing specified mass accuracy
MS Scan Power
MSn, for n = 1 through 10
Thermo Scientific™ EASY-ETD™ Ion Source
• Generates fluoranthene anions for electron transfer dissociation (ETD)
• Townsend discharge ionization is extremely stable and robust
• Compact size, located entirely within the footprint of the instrument
• Active reagent ion filtering using mass-resolving quadrupole
Thermo Scientific™ EASY-IC™ Ion Source
• Generates internal calibrant ions for real-time mass calibration on every spectrum
• Provides <1 ppm RMS mass accuracy
Synchronous Precursor Selection
Up to 15 precursors per MS2 scan, for MS3 analysis only
Multiplexing Using Ion-Routing Multipole
Up to 10 precursors per scan using quadrupole mass filter
Polarity Switching
One full cycle in 1.1 sec (one full scan in positive mode and one full scan in negative mode at resolution setting of 35,000)
